Recent studied have suggested that endometriosis (EM) in linked to systemic chronic inflammation, atherogenic lipid profile and oxidative stress [1]. As well known, all these risk factors play a key role in the pathogenesis of atherosclerotic coronary artery disease (CAD). Currently, no larger and/or randomized clinical studies have assessed the real incidence of cardiovascular (CV) events in patients with endometriosis. However, different authors have suggested that women with EM are at higher risk of CAD [2,3].