European Journal of Internal Medicine

February 2018

27 Articles

No Section

Recurrent and persistent pneumonia

2 February 2018
Author(s): Hiromichi Hara, Kazuyoshi Kuwano, Shohei Mori

A 60-year-old man presented to our department for investigation of pulmonary opacity detected by Chest Computed Tomography (CT) at medical checkup. He had no clinical symptoms. Chest CT revealed a... more

Predicting resistant etiology in hospitalized patients with blood cultures positive for Gram-negative bacilli

6 February 2018
Author(s): Marco Falcone, Giusy Tiseo, Francesco Dentali, Micaela La Regina, Emanuela Foglia, Maurizia Gambacorta, Elisabetta Garagiola, Giorgio Bonardi, Pierangelo Clerici, Fabrizio Colombo, Alessio Farcomeni, Ercole Concia, Salvatore Corrao, Mauro Campanini, Antonino Mazzone

To develop a risk-scoring tool to predict multidrug-resistant (MDR) etiology in patients with bloodstream infections (BSI) caused by Gram-negative bacilli (GNB).

Factors reducing omalizumab response in severe asthma

3 February 2018
Author(s): B. Sposato, M. Scalese, M. Milanese, S. Masieri, C. Cavaliere, M. Latorre, N. Scichilone, A. Matucci, A. Vultaggio, A. Ricci, A. Cresti, P. Santus, A. Perrella, P.L. Paggiaro

Despite adding Omalizumab to conventional therapy, several severe asthmatics still show poor disease control. We investigated the factors that may affect a reduced Omalizumab response in a large... more

Are there ways to improve the citations of a scientific paper?

3 February 2018
Author(s): E. Bartoli

The expansion of scientific publications makes more difficult the mining of relevant information necessary for a productive appraisal of authors' work, scientific interaction and exchange. Papers... more

Editorial

How to win space in medical journals: Bits and tips

10 February 2018
Author(s): Pier Mannuccio Mannucci

I chose to convey to the readership a few words not only on the achievements of the European Journal of Internal Medicine and the strategies implemented by me and the other editors for the disposal... more

Letter to the Editor

Violence against doctors: A pandemic in the making

3 February 2018
Author(s): Kanjaksha Ghosh

“No physician, however conscientious or careful can tell what day or hour he may not be the object of some undeserved attack, malicious accusation, black mail or suit for damages…”‘Assaults upon... more

The Internal Medicine and Assessment of Gender Differences in Europe (IMAGINE): The new European Federation of Internal Medicine initiative on sex and gender medicine

5 February 2018
Author(s): Alberto M. Marra, Ewelina Biskup, Valeria Raparelli, On behalf of The IMAGINE working group

The evidence that women and men are different is arguably as old as human life, yet basic research studies are performed exclusively in male animals and women are largely excluded from clinical... more

Impact of revascularization procedures on Doppler parameters in patients with atherosclerotic renal artery stenosis

5 February 2018
Author(s): Biagio Barbano, Antonietta Gigante, Marco Proietti, Edoardo Rosato, Rosario Cianci

Atherosclerotic renal artery stenosis (ARAS) represents 1% to 2% of all cases of secondary hypertension in the general population, rising up to 5.8%in patients ≥65 years old [1].

Artificial intelligence in internal medicine: Between science and pseudoscience

7 February 2018
Author(s): Henri-Corto Stoeklé, Philippe Charlier, Christian Hervé, Jean-François Deleuze, Guillaume Vogt

When faced with new, complex phenomena, humans frantically seek to predict their impact on the individual and society. The more complex the phenomenon, the more difficult it is to understand rapidly... more

Hospital mortality scores are unduly influenced by changes in the number of admissions

10 February 2018
Author(s): Rodney P. Jones, Rodney Jones

Any hospital doctor will point out that length of stay (LOS) is a far better indicator of patient acuity than diagnosis. So why do hospital doctors continue to be harassed over supposed changes in... more

Shortening antibiotic duration for community acquired pneumonia

14 February 2018
Author(s): Luis Melo, Susana Oliveira

For the last 20 years multi-resistant strains have changed the paradigm of in-hospital antibiotic prescription, forcing physicians to prescribe more broad-spectrum antibiotics. This selective... more

Significance of macro creatine kinase in admitted patients

15 February 2018
Author(s): Ami Schattner, Ina Dubin

High molecular mass forms have been reported for many serum enzymes measured in clinical laboratories. They are described as either type-1 (a normal enzyme complexed with an immunoglobulin by an... more

Molecular imaging should have played a role

17 February 2018
Author(s): Oscar M.P. Jolobe

In their account of the prognostic implications of negative echocardiography in infective endocarditis (IE) the authors made the observation that “molecular imaging may have provided additional... more

Original Article

Epidemiological characteristics, safety and efficacy of medical cannabis in the elderly

2 February 2018
Author(s): Ran Abuhasira, Lihi Bar-Lev Schleider, Raphael Mechoulam, Victor Novack

There is a substantial growth in the use of medical cannabis in recent years and with the aging of the population, medical cannabis is increasingly used by the elderly. We aimed to assess the... more

Differential diagnosis of unexplained falls in dementia: Results of “Syncope & Dementia” registry

2 February 2018
Author(s): Enrico Mossello, Alice Ceccofiglio, Martina Rafanelli, Angela Riccardi, Chiara Mussi, Giuseppe Bellelli, Franco Nicosia, Mario Bo, Daniela Riccio, Anna Maria Martone, Assunta Langellotto, Elisabetta Tonon, Gabriele Noro, Pasquale Abete, Andrea Ungar

Dementia patients have an increased risk of fall, and some of them might suffer from undiagnosed syncope. The present analysis aimed at identifying predictors of differential diagnosis between... more

Prognostic implications of a negative echocardiography in patients with infective endocarditis

4 February 2018
Author(s): Lourdes Vicent, Hugo González Saldivar, Emilio Bouza, Patricia Muñoz, Gregorio Cuerpo, Aristides de Alarcón, Bárbara Vidal, Manuel Cobo, Miguel Ángel Goenaga, Fernando Carrasco-Chinchilla, Miguel Montejo, Juan Gálvez-Acebal, Carmen Hidalgo-Tenorio, David Vinuesa-García, Manuel Martínez-Sellés, GAMES investigators (Appendix 1)

Echocardiography plays an important role in infective endocarditis (IE) diagnosis according with the modified Duke criteria. We evaluated the implications of a positive echocardiography in the... more

Association of non-immediate drug hypersensitivity with drug exposure: A case control analysis of spontaneous reports from a Tunisian pharmacovigilance database

4 February 2018
Author(s): Amel Chaabane, Najeh Ben Fadhel, Zohra Chadli, Haifa Ben Romdhane, Nadia Ben Fredj, Naceur A. Boughattas, Karim Aouam

To assess delayed-type cutaneous reactions (DTCRs) related to drugs, using a case-control approach to qualify drug risks.

Impaired renal function is associated with adverse outcomes in patients with chest pain discharged from internal medicine wards

5 February 2018
Author(s): Guy Topaz, Wesal Gharra, Alon Eisen, Alon Y. Hershko, Lotan Shilo, Gil Beeri, Yona Kitay-Cohen, David Pereg

Assessment of chest pain is one of the most common reasons for hospital admissions in internal medicine wards. However, little is known regarding predictors for poor prognosis in patients discharged... more

Pleural effusions in acute decompensated heart failure: Prevalence and prognostic implications

7 February 2018
Author(s): José Luis Morales-Rull, Silvia Bielsa, Alicia Conde-Martel, Oscar Aramburu-Bodas, Pau Llàcer, Miguel Angel Quesada, Iván Suárez-Pedreira, Luis Manzano, Manuel Montero-Pérez Barquero, José M. Porcel, RICA Investigators group

The incidence of pleural effusions (PEs) in acute decompensated heart failure (ADHF) is not well established. We aimed to determine their prevalence, clinical characteristics and prognostic... more

The use of cerebral imaging for investigating delirium aetiology

7 February 2018
Author(s): Zina Hijazi, Peter Lange, Rosie Watson, Andrea B. Maier

This study aims to investigate the frequency and patterns of use of cerebral imaging in delirium and to describe pathological changes associated with delirium using computed tomography (CT) and... more

Newer glomerular filtration rate estimating equations for the full age spectrum based on serum creatinine and cystatin C in predicting mortality in patients with ischemic stroke

9 February 2018
Author(s): Tanja Hojs Fabjan, Meta Penko, Radovan Hojs

Renal dysfunction is associated with increased risk of mortality. The novel Full Age Spectrum (FAS) equations estimating the glomerular filtration rate (GFR) based on serum creatinine (FAScrea) and... more

Postoperative pneumonia among patients with and without COPD in Spain from 2001 to 2015

13 February 2018
Author(s): Javier de Miguel-Díez, Ana López-de-Andrés, Valentín Hernández-Barrera, Isabel Jiménez-Trujillo, Manuel Méndez-Bailón, José María de Miguel-Yanes, Rodrigo Jiménez-García

To describe and compare incidence, characteristics and outcomes of postoperative pneumonia among patients with or without COPD.

External validation of a decision tree early warning score using only laboratory data: A retrospective review of prospectively collected data

14 February 2018
Author(s): Tara E. Holm Atkins, Malin C. Öhman, Mikkel Brabrand

Early warning scores (EWS) have been developed to identify the degree of illness severity among acutely ill patients. One system, The Laboratory Decision Tree Early Warning Score (LDT-EWS) is wholly... more

A proposed Oxford classification-based clinicopathological nomogram for predicting short-term renal outcomes in IgA nephropathy after acute kidney injury

3 February 2018
Author(s): Ling Zhang, Xiaodong Zhuang, Xinxue Liao

This study aimed to investigate the effect of acute kidney injury (AKI) on the progression of renal disease and to develop a clinico-pathological nomogram to predict the renal outcome of IgA... more

Geriatrician-performed comprehensive geriatric care in older adults referred to an outpatient community rehabilitation unit: A randomized controlled trial

3 February 2018
Author(s): Dmitri Zintchouk, Merete Gregersen, Torsten Lauritzen, Else Marie Damsgaard

Older adults make increasing demands on all sectors of the healthcare system. We investigated the effect of geriatrician-performed comprehensive geriatric care (CGC) in older adults referred to an... more

Review Article

The role of gut microbiota in Clostridium difficile infection

7 February 2018
Author(s): Michael Samarkos, Elpida Mastrogianni, Olga Kampouropoulou

Clostridium difficile infection has emerged as a major health problem. Because it is a spore-forming microorganism, C. difficile is difficult to eradicate and recurrences of the infection are... more