Published: 15 January 2017
Author(s): Kalliopi Zachou, Stella Gabeta, Zakera Shums, Nikolaos K. Gatselis, George K. Koukoulis, Gary L. Norman, George N. Dalekos
Issue: January 2017
Section: Original Article

Recently we have shown that cartilage oligomeric matrix protein (COMP), a fibrillar collagen assembly regulator, is strongly associated with cirrhosis and hepatocellular carcinoma progression. Therefore, we assessed whether serum COMP levels can be used as a non-invasive fibrosis marker in patients with chronic viral hepatitis (CVH) and compared this marker with standard methods for disease stage assessment [histology, transient elastography (TE), APRI, FIB-4].

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