Published: 14 September 2021
Author(s): Vinay Guduguntla, Rita F. Redberg
Issue: January 2022
Section: Review Article

Coronary artery disease is common, affecting more than an estimated 125 million people worlwide [1,2]. More than half of all patients with coronary artery disease (CAD) have anginal symptoms [3]. Medical therapy, in conjunction with lifestyle changes, is the recommended first line intervention for all patients with stable coronary artery disease [4,5]. Optimal medical therapy (OMT) as defined in the guidelines and most major trials has been a combination of medications aimed at reducing cardiac events and anginal symptoms.

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