Published: 13 March 2022
Author(s): Pasquale Mone, Antonella Pansini, Salvatore Frullone, Antonio de Donato, Veronica Buonincontri, Paolo De Blasiis, Anna Marro, Maria Morgante, Antonio De Luca, Gaetano Santulli
Issue: May 2022
Section: Original article

Frailty is a biological syndrome of decreased physiological reserves with incremented vulnerability to stressors and its prevalence among older adults has been estimated at ∼10% [1]. Hypertension is a prevailing comorbidity in older adults and its incidence increases with age [2,3]. Vascular dementia (VD) and Alzheimer's Disease (AD) are among the main causes of dementia and/or mild cognitive impairment (MCI) in older adults with or without frailty [4]. Despite these shreds of evidence and despite the emerging interest in geriatric conditions, the actual correlation between physical and cognitive impairment in physically frail patients remains unclear.

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