Cirrhosis is the end stage of various diseases of the liver. The leading causes of liver diseases are hepatitis B and C viral infections (HBV and HCV), alcohol consumption and cryptogenetic disease [1]. Thanks to the advent of nucleot(s)ide HBV analogs and direct anti HCV agents, the long-term survival of patients affected by liver cirrhosis has improved significantly in recent years [2–4]. Nevertheless, even in case of viral suppression or viral clearance, patients with liver cirrhosis remain at risk for decompensation, hepatocellular carcinoma (HCC) and death.
