Published: 17 May 2020
Author(s): Antonio Spanevello, Bianca Beghé, Dina Visca, Leonardo M. Fabbri, Alberto Papi
Issue: August 2020
Section: Review Article

Cough is a physiologic defense mechanism for clearing the airways of secretions, exudate, or foreign bodies. Its mechanisms are well known, with afferent, central, and efferent nervous pathways that are complex and may explain the multiple mechanisms of both physiologic cough and pathologic cough, and particularly chronic cough [1,2]. Cough, especially chronic cough, is one of the most frequent symptoms requiring medical attention, and is often not due to identifiable causes. Chronic cough in children has different characteristics from that in adults and, in contrast to adults, is mostly linked to underlying identifiable causes [3].


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