Published: 12 June 2019
Author(s): Martina Chirra, Luca Marsili, Simone Gallerini, Elizabeth G. Keeling, Roberto Marconi, Carlo Colosimo
Issue: June 2019
Section: Narrative Review

Paraneoplastic syndromes include, by definition, any symptomatic and non-metastatic condition associated with a neoplasm. Paraneoplastic movement disorders are a heterogeneous group of syndromes encompassing both hyperkinetic and hypokinetic conditions, characterized by acute/sub-acute onset, rapidly progressive evolution, and multifocal localizations with several overlapping features. These movement disorders are immune-mediated, as shown by the rapid onset and by the presence of antineuronal antibodies in biological samples of patients, fundamental for the diagnosis.


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