Published: 9 July 2022
Author(s): Gian Luca Erre, Fabio Cacciapaglia, Garifallia Sakellariou, Andreina Manfredi, Elena Bartoloni, Ombretta Viapiana, Marco Fornaro, Alberto Cauli, Arduino Aleksander Mangoni, Richard John Woodman, Bianca Lucia Palermo, Elisa Gremese, Giacomo Cafaro, Valeria Nucera, Caterina Vacchi, Francesca Romana Spinelli, Fabiola Atzeni, Matteo Piga, “Cardiovascular, Obesity and Rheumatic Disease Study (CORDIS) Group” of the Italian Society of Rheumatology (SIR)
Issue: October 2022
Section: Original article

Rheumatoid arthritis (RA) is associated with an increased risk of cardiovascular disease compared with the general population [1]. The increased risk of cardiovascular disease in patients with RA is due to the composite effect of genetic predisposition, traditional cardiovascular risk factors, and the presence of chronic oxidative stress [2–4] and systemic pro-inflammatory state. Cardiovascular disease in RA population develops through multiple mechanisms, including accelerated endothelial dysfunction, early arterial stiffening, modifications of central hemodynamics, and premature atherosclerosis [5–7].


Stay informed on our latest news!


This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.