Published: 11 May 2020
Author(s): Dimitrios Sagris, Ioannis Leventis, Georgios Georgiopoulos, Eleni Korompoki, Konstantinos Makaritsis, Konstantinos Vemmos, Haralampos Milionis, Gregory Y.H. Lip, George Ntaios
Section: Original article

Aspirin was recommended in the past as an alternative to oral anticoagulation for the prevention of thromboembolism in patients with atrial fibrillation (AF) and a CHA2DS2-VASc score of 1 [1]. The supposed beneficial effect of aspirin compared to placebo/control was supported by a single randomized controlled trial (RCT) which was prematurely terminated, with marked internal heterogeneity for the aspirin effect between anticoagulation-eligible and anticoagulation-ineligible patients [2,3].


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