Published: 26 May 2020
Author(s): Samarthkumar Thakkar, Rajkumar Doshi, Mariam Shariff, Igor Pedreira Vaz, Devina Adalja, Monil Majmundar, Ashish Kumar
Section: Letter to the Editor

Despite significant furtherance in the medical management of heart failure (HF), readmission and mortality following HF hospitalization are significantly high. Traditionally, optimization of medical therapy, which includes angiotensin-converting enzyme (ACE) inhibitors, beta-blockers, diuretics, and aldosterone antagonist is mainly guided by symptomatology and patient tolerance. Left ventricular wall stretch provokes secretion of plasma brain natriuretic peptide (BNP) and N-terminal pro BNP (NT-pro BNP), which are proposed as markers to guide and optimize medical therapy.


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