April 2023
29 ArticlesNo Section
Intravenous pulse methylprednisolone for the treatment of severe COVID-19
Corticosteroids still represent one of the cornerstone treatment options for subjects hospitalized with coronavirus disease 2019 (COVID-19), especially for those suffering from a severe form of the... more
Commentary
Lung ultrasound must be the first-line image technique in COVID-19 patients
Lung ultrasound (LUS) is a paradigm of Point of Care Ultrasound values. First, it has no “owner” because its use has been developed by different specialties such as Intensive Care Medicine, Emergency... more
De-escalation in intensity or duration of dual antiplatelet therapy in patients with coronary artery disease: More than alternative treatment options
Antithrombotic therapy represents the mainstay of pharmacological treatments in patients with acute or chronic coronary syndrome (CCS) undergoing percutaneous coronary intervention (PCI) [1]. Since... more
Endovascular therapy for basilar occlusion: Is there robust evidence?
The combined rate of mortality and severe disability for patients with acute basilar artery occlusion is as high as 90% [1,2]. Observational studies report that with revascularization therapies this... more
Internal Medicine Flashcard
Hepatobiliary diseases
A 60-year-old woman had been diagnosed with Gallstone five years previously. The patient's symptoms were relieved following anti-inflammatory therapy for one week. She was now admitted to... more
Zosteriform erythematous rash
A 70-years-old male presented with unilateral rash below the right axilla of one-month duration. The patient gave history of cough with shortness of breath for the last two years and pain in the... more
Letter to the Editor
Treatment of acute alcohol intoxication: The role of metadoxine
Dear Editor,
Evolution of the SARS-CoV-2 epidemic: From genomic surveillance to new health needs
Dear editor
Lower risks of incident colorectal cancer in SGLT2i users compared to DPP4i users: A propensity score-matched study with competing risk analysis
Dear Editor,
Long-term prognostic capacity of multi-comorbid indices in chronic obstructive pulmonary disease
Dear Editor,
Risk of obstructive sleep apnea in idiopathic pulmonary fibrosis
To the editor,
Timeline analysis of clinical severity of COVID-19 in the general population
We read with interest the recent article of Giacomelli et al. [1], who showed that the main characteristics of patients hospitalised with coronavirus disease 2019 (COVID-19) have substantially... more
Lack of efficacy of Interferon β-1a in COVID-19 patients with mild to moderate pneumonia
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome virus 2 (SARS-CoV-2), poses an unprecedented threat for global health. Even in the context of intensified vaccine... more
Hypersensitivity reactions associated with iron isomaltoside and ferric carboxymaltose
Dear editor,
Hip involvement in familial Mediterranean fever
Familial Mediterranean fever (FMF) is a monogenic autoinflammatory disorder that is linked to homozygous mutations of the MEFV gene [1]. The field of FMF is expanding as many patients with FMF... more
Aspirin and P2Y12 inhibitors in treating COVID-19
Dear Editor,
Endovascular Thrombectomy in Basilar-Artery Occlusion Stroke
Dear Editor;
Original Article
Prevalence of non-alcoholic fatty liver disease in a multicentre cohort of people living with HIV in Spain.
Since the beginning of the history of HIV infection, liver disease has been one of the major causes of morbidity and mortality in people living with HIV (PLWH) [1]. Even though the emergence of the... more
Functional outcome after cardiac rehabilitation and its association with survival in heart failure across the spectrum of ejection fraction
Heart failure (HF) is an increasingly prevalent clinical syndrome and a major cause of cardiovascular mortality and morbidity [1,2]. Functional disability and loss of independence are hallmark... more
Trends in prevalence and all-cause mortality of metabolic dysfunction-associated fatty liver disease among adults in the past three decades: Results from the NHANES study
Non-alcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease, with an overall prevalence of 25%–32.4% worldwide, imposing a considerable health and economic burden [1,2]. Given... more
Circulating GDF-15 in relation to the progression and prognosis of chronic kidney disease: A systematic review and dose-response meta-analysis
Chronic kidney disease (CKD) has been a health problem worldwide that is characterized by the high incidence, poor prognosis, and large healthcare cost [1]. Since CKD has insidious onset and atypical... more
Higher diagnostic yield of 18F-FDG PET in inflammation of unknown origin compared to fever of unknown origin
18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) imaging often plays an important role in the workup of fever of unknown origin (FUO) and inflammation of unknown origin (IUO),... more
The efficacy and safety of tacrolimus in patients with dermatomyositis/polymyositis: A meta-analysis and systematic review
Idiopathic inflammatory myopathies (IIMs) are a group of autoimmune inflammatory muscle disorders characterized by muscle weakness and multisystem involvement, especially in skin and lungs.... more
Comparison of missed adenomas in deep-sedated and unsedated colonoscopy: A multicenter retrospective study
According to the Global Cancer Report 2020, colorectal cancer ranks third in incidence and second in mortality of cancer-related diseases worldwide [1]. Colonoscopy is currently considered the gold... more
The clinical presentation of syncope influences the head-up tilt test responses
The nitroglycerin (NTG) potentiated head-up tilt test (HUTT) positivity rate was about 1.5 times higher in patients with classical vasovagal (VVS) compared to those with non-classical VVS. The higher... more
Efficacy of endovascular therapy for basilar and vertebral artery occlusion: A systematic review and meta-analysis of randomized controlled trials
The best management for acute basilar artery occlusion (BAO) has increasingly been clarified by recent randomized controlled trials (RCTs). We conducted a systematic review and meta-analysis of RCTs... more
Long-term lung ultrasound follow-up in patients after COVID-19 pneumonia hospitalization: A prospective comparative study with chest computed tomography
From December 2019, the medical scenario has been characterized by the SARS-CoV-2 pandemic that put a strain on the healthcare systems all around the world. Human-to-human aerosol transmission as... more
Review Article
Pathophysiology of cough with angiotensin-converting enzyme inhibitors: How to explain within-class differences?
Angiotensin-converting enzyme inhibitors (ACEi) are largely used for the prevention and treatment of cardiovascular and renal diseases [1]. The rationale supporting the use of ACEi is based on... more
De-escalation of antiplatelet therapy in patients with coronary artery disease: Time to change our strategy?
Since more than two decades, dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor is considered the gold standard for patients with acute coronary syndrome (ACS) as well as... more