A growing body of evidence [1–6] suggests that some patients who survive an acute SARS-CoV-2 viral infection (COVID-19) may experience persistent symptoms for months, resulting in a clinical syndrome known as Long-COVID or PASC (Post-Acute Sequelae of COVID). These symptoms, including fatigue, shortness of breath, diffuse pain, orthostatic intolerance with excessive tachycardia upon standing, palpitations, memory difficulties, brain fog and others, may reflect underlying abnormalities in autonomic nervous system functioning and negatively impact overall quality of life [QoL] [3–5].
