In their recent article, Real de Asua et al. [1] identified the most common conditions diagnosed in a population of Spanish adults with Down syndrome (DS). DS has historically represented a pediatric condition because of its shortened life span. However, in the last decades, due to increased survival, adults and elders with DS have become an emerging new population with particular characteristics, worthy of care and research. Indeed, life expectancy of persons with DS has dramatically increased, from nineyears in 1929 [2] to 60years in 2002 [3–5].
