January 2019

20 Articles

No Section

Persistent FDG/PET CT uptake in idiopathic retroperitoneal fibrosis helps identifying patients at a higher risk for relapse

31 January 2019
Author(s): Gabriel Morin, Arthur Mageau, Khadija Benali, Remi Bertinchamp, Eve Piekarski, Quentin Raimbourg, Jean-Francois Alexandra, Tiphaine Goulenok, Damien van Gysel, Thomas Papo, Karim Sacre

The aim of this study was to evaluate the prognostic value of persistent retroperitoneal fibrosis FDG uptake using FDG/PET CT in patients with idiopathic retroperitoneal fibrosis (IRF).

Performance of the CHA2DS2-VASc score in predicting new onset atrial fibrillation during hospitalization for community-acquired pneumonia

25 January 2019
Author(s): Filippo Pieralli, Beatrice Biondo, Vieri Vannucchi, Marco Falcone, Elisa Antonielli, Giulia De Marzi, Carlotta Casati, Lucia Maddaluni, Carlo Nozzoli, Iacopo Olivotto

Cardiovascular events are common during hospitalization for community-acquired pneumonia (CAP), with new onset atrial fibrillation (NOAF) being the second most relevant complication. In this study,... more

Differences in left ventricular geometry in hypertensive African-Europeans and Caucasian patients

25 January 2019
Author(s): Laurence Ejiofor, Concetta Di Nora, Eugenio Cervesato, Iulian Cosei, Andreea Ravasel, Bogdan A. Popescu, Francesco Antonini-Canterin

There are data showing race-related differences regarding left ventricular (LV) geometry in hypertensive patients. Several authors reported that concentric remodeling is the most common remodeling... more

Risk of bleeding in hospitalized patients on anticoagulant therapy: Prevalence and potential risk factors

24 January 2019
Author(s): Albert R. Dreijer, Jeroen Diepstraten, Rolf Brouwer, F. Nanne Croles, Esther Kragten, Frank W.G. Leebeek, Marieke J.H.A. Kruip, Patricia M.L.A. van den Bemt

Bleeding is the most important complication of treatment with anticoagulant therapy. Although several studies have identified risk factors of bleeding in outpatients, no studies have been performed... more

Insomnia symptoms in primary care: A prospective study focusing on prevalence of undiagnosed co-morbid sleep disordered breathing

24 January 2019
Author(s): H. Hilmisson, E. Sveinsdottir, Neale Lange, S. Magnusdottir

To determine prevalence of comorbid undiagnosed sleep disordered breathing (SDB) in chronic insomnia patients, using two complementary methods, one standard and one novel.

Tick-borne encephalitis in Europe: a brief update on epidemiology, diagnosis, prevention, and treatment

21 January 2019
Author(s): Niccolò Riccardi, Roberta Maria Antonello, Roberto Luzzati, Joanna Zajkowska, Stefano Di Bella, Daniele Roberto Giacobbe

Tick-borne encephalitis (TBE) is an emerging health threat that is spreading in many parts of Europe. The mix of socio-economical, ecological and climatic factors as well as the presence of more... more

Big trouble with temporary tattoos

10 January 2019
Author(s): James M. Carr, Ajoy Bardhan, Tracey M. Finch

A 25 year old hairdresser was referred acutely following the development of pruritic pink papules and subsequently bullae, 24 h after the application of a temporary black henna tattoo to the dorsum... more

Direct oral anticoagulants vs non-vitamin K antagonist in atrial fibrillation: A prospective, propensity score adjusted cohort study

9 January 2019
Author(s): Marco Marietta, Federico Banchelli, Piercamillo Pavesi, Cesare Manotti, Roberto Quintavalla, Tiziana Sinigaglia, Giuliana Guazzaloca, Corrado Pattacini, Stefano Urbinati, Vincenzo Livio Malavasi, Giuseppe Boriani, Claudio Voci, Roberto D'Amico, Nicola Magrini

Oral anticoagulants directly inhibiting Factor IIa o Factor Xa (DOAC) have been marketed in Italy for the prevention of cardiac embolism in patients affected by non-valvular atrial fibrillation (NVAF... more

A painful rash after chemotherapy

4 January 2019
Author(s): Shing Ching, Yim Kwan Lam

A 76-year-old man presented with a painful rash one week after receiving chemotherapy consisting of cetuximab, oxaliplatin and fluorouracil for metastatic colon cancer. Physical exam was notable for... more

Hepatic-pulmonary disease

3 January 2019
Author(s): Juan Carlos Cataño, Diana Karina Agredo

A 42-year-old Colombian woman, who has lived her entire life on a farm, has a 12 years history of intermittent episodes of sharp left thoracic pain, associated with cough and hemoptysis, for which... more

Internal Medicine Flashcard

The hand of respiratory failure

15 January 2019
Author(s): Federica De Giacomi, Narat Srivali

73-year-old man presented to our institution with shortness of breath, diffuses myalgia and noticed the significant change of his hands. Physical examination was remarkable for bilateral crackle at... more

A suspicious fracture

3 January 2019
Author(s): Agostino Gaudio, Andrea Ruben Murabito, Pietro Castellino

A 67 year-old woman referred to our Metabolic Bone Diseases Outpatient Clinic for non-traumatic left thigh pain occurring in the last few weeks. She had been diagnosed with osteoporosis in 2004 and... more

Letter to the Editor

Cardiovascular events and de novo AF following Legionnaires disease

24 January 2019
Author(s): João Ferreira-Coimbra, Marta Soares Carreira, Ana Luísa Cunha, Sandra Rebelo, José Manuel Pereira

Cardiovascular (CV) diseases are a worldwide major cause of death. This fact relates to a number of risk factors [1], but infection might be pointed as one of utmost importance as it triggers... more

Recommending marijuana use: Violation of the Hippocratic aphorism of “do good or do no harm”

24 January 2019
Author(s): Antonis S. Manolis, Theodora A. Manolis

Legalization of medical or recreational use of marijuana presupposes that all drug-formulations have been tested and proven safe. However, this has not been the case with this substance, and to be... more

In reply to “Small, however significant differences in the definition of physical frailty and sarcopenia”

22 January 2019
Author(s): Riccardo Calvani, Anna Picca, Francesco Landi, Matteo Cesari, Emanuele Marzetti

We thank Dr. Yilmaz and colleagues [1] for their comment that allows us to further clarify a major strength of the BIOSPHERE study [2]. Many operational definitions of frailty exist, each of them... more

Horizontal vs. vertical dose reduction of direct oral anticoagulants in patients with non-valvular atrial fibrillation: definition and implications for practice

19 January 2019
Author(s): Andrea Rubboli

Post-marketing surveillance is being showing a widespread use of the lower doses of direct oral anticoagulants (DOACs), namely dabigatran 110 mg, rivaroxaban 15 mg, apixaban 2.5 mg, and edoxaban 30 ... more

Cancer and atrial fibrillation. Author's reply

18 January 2019
Author(s): Vincenzo Livio Malavasi, Marco Marietta, Gregory Y.H. Lip, Giuseppe Boriani

We appreciate the interest of Sorigue in our paper [1,2]. In his comments [2], he underlines several interesting points relevant to the management of atrial fibrillation (AF) in cancer patients.

Original Article

Comorbidity assessment for mortality risk stratification in elderly patients with acute coronary syndrome

31 January 2019
Author(s): Juan Sanchis, Meritxell Soler, Julio Núñez, Vicente Ruiz, Clara Bonanad, Francesc Formiga, Ernesto Valero, Manuel Martínez-Sellés, Francisco Marín, Arancha Ruescas, Sergio García-Blas, Gema Miñana, Emad Abu-Assi, Héctor Bueno, Albert Ariza-Solé

The Charlson's is the most used comorbidity index. It comprises 19 comorbidities, some of which are infrequent in elderly patients with acute coronary syndrome (ACS), while some others are... more

Antidepressant prescription in acute myocardial infarction is associated with increased mortality 1 year after discharge

28 January 2019
Author(s): Nadia Fehr, Fabienne Witassek, Dragana Radovanovic, Paul Erne, Milo Puhan, Hans Rickli

To assess the impact of antidepressant (AD) prescription at discharge on 1-year outcome of patients presenting with acute myocardial infarction (AMI) in Switzerland.


Impact of Daylight Saving Time on circadian timing system: An expert statement

5 January 2019
Author(s): M. Meira e Cruz, M. Miyazawa, R. Manfredini, D. Cardinali, J.A. Madrid, R. Reiter, J.F. Araujo, R. Agostinho, D. Acuña-Castroviejo

Even though that in the very beginning of Daylight Saving Time (DST) policy, standards were decided individually by each country, and were not regulated, most European member States have... more


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