Published: 21 April 2020
Author(s): Manuel Rubio-Rivas, Xavier Corbella
Issue: July 2020
Section: Original article

Sarcoidosis is a multisystem granulomatous disease with high variability and sometimes unpredictable behavior. This great variability necessitates the search for clinical patterns of observed phenotypic variables to help in care management [1-3]. However, definition of a true phenotype requires a consistent natural history, similar clinical and physiological characteristics, underlying pathobiology with identifiable biomarkers and genetics, and a predictable response to general and specific therapies [4].


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