March 2017

20 Articles

No Section

Impact of forgoing care because of costs on the quality of diabetes care: A three-year cohort study

12 March 2017
Author(s): Patricia C. Rosselet, Emilie Zuercher, Jérôme Pasquier, Bernard Burnand, Isabelle Peytremann-Bridevaux

Forgoing care because of costs is a frequent situation in many countries, with estimated prevalences going from 4% to 30% [1–6]. It can be defined as a decision of not seeking care when needed... more

Developments in Internal Medicine

Higher uric acid serum levels are associated with better muscle function in the oldest old: Results from the Mugello Study

22 March 2017
Author(s): R. Molino-Lova, F. Sofi, G. Pasquini, F. Vannetti, S. Del Ry, C. Vassalle, M. Clerici, S. Sorbi, C. Macchi

Sarcopenia is the progressive loss of muscle mass and strength that occurs with advancing age and plays a pivotal role in the causal pathway leading to frailty, disability and, eventually, to death... more


Homeopathy provided by a national health service: Only in Italy?

23 March 2017
Author(s): Silvio Garattini, Pier Mannuccio Mannucci

Homeopathy was born in Germany around the end of the eighteenth century through the work of Samuel Hahnemann (1755–1843). In the context of a medical era characterized by remedies such as... more

Letter to the Editor

Antithrombotic therapy in patients with atrial fibrillation undergoing coronary stenting: Suggested strategies tailored to an integrated evaluation of different risk profiles

29 March 2017
Author(s): Giuseppe Patti, Andrea Rubboli

The optimal antithrombotic therapy for patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention with stent (PCI-S) is still undetermined [1,2]. Current recommendations,... more

Do opinion articles attract more social attention than original research, relative to their citation counts?

25 March 2017
Author(s): Rafael Dal-Ré, Ignacio Mahillo-Fernández, Michael Thelwall

Scientific findings are disseminated as original investigation articles but influential medical journals also publish opinion articles. Although opinion articles provide less citable information than... more

Art and historical personages with probable Graves disease

24 March 2017
Author(s): Antonio V. Sterpetti, Marco Ventura

Graves disease, also known as toxic diffuse goiter, was described separately by Dr. Robert J Graves and Dr. Karl Adolph von Basedow in 1835 and 1840 respectively. Historians give credit for the first... more

Commitment to life and the right to die

20 March 2017
Author(s): Walter G. Sannita

Repeated polling by Gallup has found since 1973 majorities in favor of legal doctor-assisted dying, with widespread preference for state regulation and disfavor for any patient/doctor's private... more

Epidemiology of cystic fibrosis-related diabetes in Madrid (Spain) and frequency of hospitalization

20 March 2017
Author(s): Ana Clara Zoni, M. Felicitas Domínguez-Berjón, María D. Esteban-Vasallo, Juan Manuel Sendra, Jenaro Astray-Mochales

Advances in care in Cystic fibrosis (CF) patients have improved the survival and the quality of life, but endocrine comorbidities gained greater significance [1]. CF-related diabetes (CFRD) is the... more

Differences in short and long-term survival between males and females with new-onset heart failure: A retrospective cohort study

20 March 2017
Author(s): Gabriel Chodick, Dahlia Weitzman, Robert O. Blaustein, Varda Shalev, Lori D. Bash

A meta-analysis of 31 studies (MAGGIC) [1] has shown that women with heart failure (HF) have better survival than men. However, these studies were limited by selective patient populations (e.g.... more

Should a scientist be prevented from publishing in a journal for which he works?

18 March 2017
Author(s): P. Charlier, S. Deo, L. Brun

Should scholars publish in the journal they are working for? In other words, is it legitimate to publish in his own journal, that is to say submit and/or co-sign in a journal of which one is editor-... more

Experience of using ISGTL-2 in patients with DM2 and HIV infection

18 March 2017
Author(s): M. Dolores García de Lucas, Julián Olalla

It is estimated that up to 14% of patients with HIV have diabetes mellitus (DM), which is a determinant risk factor for the development of cardiovascular disease [1]. The therapeutic regimen is the... more

Bacterial infections and NSAIDs exposure? Seek septic complications

13 March 2017
Author(s): Paul Le Turnier, David Boutoille, Caroline Joyau, Gwenaelle Veyrac, Nathalie Asseray

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely consumed. Some authors suggested a relationship between more severe infections and NSAIDs exposure, especially skin and soft tissue infections... more

Reply to: Activation and quantification of human brown adipose tissue: Methodological considerations for between studies comparisons

7 March 2017
Author(s): Lonneke Bähler, Frits Holleman, Hein J. Verberne

We thank Martinez-Tellez and co-authors for their interest in our article. Martinez-Tellez et al. are quite right in their statement that there are more factors involved in activation of human BAT... more

The association between a simple measure of QRS voltage and the in-hospital mortality of acutely ill medical patients

7 March 2017
Author(s): Martin Otyek Opio, John Kellett, Kitovu Hospital Study Group

There are multiple causes of low QRS voltage on the ECG, and often it is unexplained and considered to be a normal variant [1], occurring in 1.4% of individuals free of cardiovascular disease [2].... more

Comorbidities in heart failure with mid-range ejection fraction

1 March 2017
Author(s): Juan I. Pérez-Calvo, Claudia Josa-Laorden, Jorge Rubio-Gracia, Ignacio Giménez-López

The recent Guidelines of heart failure (HF) of the European Society of Cardiology (ESC) propose an emerging classification of HF according to left ventricular ejection fraction (LVEF) [1]. Namely,... more

Narrative Review

Oral anticoagulant therapy for older patients with atrial fibrillation: a review of current evidence

24 March 2017
Author(s): Mario Bo, Enrica Grisoglio, Enrico Brunetti, Yolanda Falcone, Niccolò Marchionni

Atrial fibrillation is more frequent in older patients, who have a higher risk of cardioembolic stroke and thromboembolism. Oral anticoagulant therapy is the standard of treatment for stroke... more

Original Article

A new method to predict hospital mortality in severe community acquired pneumonia

18 March 2017
Author(s): Xin Wang, Jianlong Jiao, Rongwei Wei, Yongli Feng, Xiuqin Ma, Yuan Li, Yue Du

The aim of this study is to develop a new method that is able to accurately predict the 28day hospital mortality in patients with severe community acquired pneumonia (SCAP) at an early stage.

Assessment of risk factors for candidemia in non-neutropenic patients hospitalized in Internal Medicine wards: A multicenter study

15 March 2017
Author(s): M Falcone, G Tiseo, C Tascini, A Russo, E Sozio, G Raponi, C Rosin, P Pignatelli, P Carfagna, A Farcomeni, R Luzzati, F Violi, F Menichetti, M Venditti

An increasing prevalence of candidemia has been reported in Internal Medicine wards (IMWs). The aim of our study was to identify risk factors for candidemia among non-neutropenic patients... more

Is HOMA-IR a potential screening test for non-alcoholic fatty liver disease in adults with type 2 diabetes?

7 March 2017
Author(s): Gala Gutierrez-Buey, Jorge M. Núñez-Córdoba, María Llavero-Valero, Javier Gargallo, Javier Salvador, Javier Escalada

Non-alcoholic fatty liver disease (NAFLD) is the commonest hepatic disease in many parts of the World, with particularly high prevalence in patients with type 2 diabetes (T2DM). However, a good... more

Review Article

Kidney disease and venous thromboembolism: Does being woman make the difference?

1 March 2017
Author(s): A Gigante, F Di Mario, A Pierucci, A Amoroso, FS Pignataro, L Napoleone, S Basili, V Raparelli

The risk of venous thromboembolism (VTE) is increased across the spectrum of chronic kidney disease (CKD), from mild to more advanced CKD, and typically characterizes nephrotic syndrome (NS). VTE... more


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