Published: 17 February 2021
Author(s): Simona Agazzi, Marco Vincenzo Lenti, Catherine Klersy, Elena Strada, Lodovica Pozzi, Laura Rovedatti, Marco Bardone, Aurelio Mauro, Martina Costetti, Stefania Costa, Federico De Grazia, Antonio Di Sabatino
Issue: May 2021
Section: Original article

According to estimates from the International Agency for Research on Cancer (2018), colorectal cancer (CRC) occurred in approximately 1.8 million patients and accounted for 900000 deaths worldwide, making it the third most commonly diagnosed malignancy and the second leading cause of cancer death [1]. Because of the slow progression from adenoma to adenocarcinoma, a substantial proportion of CRC cases can be preventable [2]. The development of effective screening tests, including faecal occult blood test and colonoscopy, has supported the implementation of CRC screening campaigns promoted by public healthcare programs [3] and scientific societies [4,5].


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