In the first half of 2021, many millions of Europeans will be offered vaccination against SARS -CoV-2. Four vaccines, two mRNA-based vaccines (Pfizer-BioNTech and NIH-Moderna) and two non-replicating viral vector-based vaccines (Oxford-AstraZeneca and Janssen) will likely be available through national health services (NHS). Should citizens accept the vaccine provided by their NHS or should they have the option of selecting the vaccine of their choice?