A 55-year-old female with a history of asthma, diabetes mellitus and hypertension presented with a 2-month history of multiple tender nodules on the bilateral lower extremities. She suffered from asthma and had been treated with, on average, 10–20mg prednisolone daily for years. Physical examination revealed multiple erythematous tender nodules, measuring 2–4cm on the bilateral lower extremities (Fig. 1, Panel A). Ulceration and purulent discharge were found in the largest nodule on the right thigh (Fig. 1, Panel A).