As far as we understand, Lilli [1] maintains that we may lessen our skepticism toward a research hypothesis following a succession of positive results. He mentions the example of a diagnostic test which unexpectedly turns out positive for a disease the clinician who ordered the test is skeptical about. This is an unlikely situation: as a rule a clinician requires a test when she/he definitely suspects the presence of a given disease on the basis of observed symptoms and signs. A corresponding condition is a clinical study testing a hypothesis with a sizable probability of being correct.
