We very appreciate these comments [1]. All of our manuscripts have been carefully and critically reviewed many times by these professional editors and experienced reviewers independently provided by these outstanding journals. Of course, each of our manuscripts was already evaluated for its scientific validity by an editor and a reviewer, without any negative or positive bias. We are most grateful that the revised manuscripts were published in these widely-praised journals, finally. Therefore, these researches should be hypothesis-driven enough and very helpful to these clinicians [2–6].