Published: 19 November 2020
Author(s): Siyu Liang, Shi Chen, Yuelun Zhang, Huijuan Zhu, Hui Pan
Issue: April 2021
Section: Letter to the editor

Dysnatremia is the most common electrolyte disorder in hospitalized patients [1]. Dysnatremia is generally classified as hyponatremia (145mmol/L). Many studies showed that hypernatremia and hyponatremia are independently associated with an increased risk of poor clinical outcomes in hospitalized patients [1, 2], while serum sodium levels between 135 mmol/L and 145 mmol/L are previously treated as normal. Recent studies have focused on the correlation between hospital mortality and sodium fluctuations, even within sodium reference ranges [3].


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