Published: 30 November 2022
Author(s): Sylvia M Brakenhoff, Roos Hoekstra, Pieter Honkoop, Robert Roomer, Jan G den Hollander, Geert Bezemer, Robert J de Knegt, Milan J Sonneveld, Robert A de Man
Section: Original article

Hepatitis B virus infection (HBV) is considered a global health threat as it is associated with liver decompensation, liver cirrhosis and primary liver cancer [1]. Worldwide, approximately 269 million individuals have a chronic active hepatitis B infection [1,2]. In the Netherlands, the prevalence of chronic hepatitis B has been estimated at 0.2-0.4%, and approximately 3.5% of the population has a resolved hepatitis B infection [3–5]. Since most HBV infections progress asymptomatically, many patients are unaware of their infection.


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