Published: 26 March 2021
Author(s): George N. Dalekos, Aggelos Stefos, Sarah Georgiadou, Vasiliki Lygoura, Anastasia Michail, George Ntaios, Anna Samakidou, George Giannoulis, Stella Gabeta, Marianna Vlychou, Efthymia Petinaki, Konstantinos Leventogiannis, Evangelos J. Giamarellos-Bourboulis, Nikolaos K. Gatselis
Issue: June 2021
Section: Original article

Aims Infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) may lead to the development of severe respiratory failure. In hospitalized-patients, prompt interruption of the virus-driven inflammatory process by using combination treatments seems theoretically of outmost importance. Our aim was to investigate the hypothesis of multifaceted management of these patients.Methods A treatment algorithm based on ferritin was applied in 311 patients (67.2% males; median age 63-years; moderate disease, n=101; severe, n=210).


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