The Coronavirus 2 (Covid-19) associated severe acute respiratory failure (ARF) has led to a huge number of admissions to intensive care units (ICU) with high fatality rates and shortage of beds. We had previously reported management and outcomes of patients with nasal/throat swabs still positive for SARSCoV-2 by polymerase chain reaction, transferred from acute care hospitals to rehabilitation facilities of northern Italy [1]. The present letter (Ethics committee approval: 2440, May 26th 2020, informed consent by patients) reports the outcome of survived critical patients undergone invasive mechanical ventilation and transferred, from March to June 2020, from ICU of Italian Regions Lombardia and Piemonte directly to step down units of three centers (Lumezzane, Pavia, Veruno) of Istituti Clinici Scientifici (ICS) Maugeri IRCCS network, referral Institutions for prolonged weaning, pulmonary rehabilitation and chronic care.