Published: 6 March 2022
Author(s): Carlo Maria Rossi, Marco Vincenzo Lenti, Antonio Di Sabatino
Issue: June 2022
Section: Review Article

Anaphylaxis is an acute, usually rapidly developing, systemic (involving multiple organs) allergic reaction and, among the various clinical forms of allergy, it is the most severe and potentially life-threatening [1]. In the last decades, an epidemiologic increase of anaphylaxis, mainly in terms of hospitalization, has been observed [2]. This is particularly the case of food allergy [3] [4]. The overall incidence of anaphylaxis varies between 50 and 112 episodes per 100.000 person-years while its prevalence is 0.3–5.1% according to various epidemiological and classification factors [5].


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