Published: 21 March 2022
Author(s): Nana Akazawa, Naoya Itoh, Masashi Ando
Issue: June 2022
Section: Internal Medicine Flashcard

A 54-year-old man presented with a chief complaint of fever and pain around the left clavicle. He had a primary germ cell tumor of the mediastinum and had been undergoing chemotherapy for approximately six months. To prevent myelosuppression, pegfilgrastim was administered after each chemotherapy session. Pegfilgrastim was administered 4 days before the onset of fever and pain. On examination, he had a body temperature of 38.1 °C and pain in the left arm. Laboratory findings showed elevated C-reactive protein level (19.4 mg/dL).


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