Published: 31 October 2019
Author(s): Jack Hirsh, John W Eikelboom, Noel C Chan
Issue: October 2019

The achievements with antithrombotic therapy over the past 50 years have been monumental and the disappointments relatively few. In this review, we will discuss, chronologically, the major developments of the two recognized classes of antithrombotics - anticoagulants and antiplatelet agents.

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