September 2018

18 Articles

No Section

Interventional pulmonology techniques in elderly patients with comorbidities

29 September 2018
Author(s): Michele Mondoni, Dejan Radovanovic, Giovanni Sotgiu, Fabiano Di Marco, Paolo Carlucci, Stefano Centanni, Pierachille Santus

Respiratory diseases are common cause of disability in the elderly and are often concomitant with other non-respiratory medical conditions. Interventional pulmonology includes advanced diagnostic and... more

Management of immune thrombocytopenia in elderly patients

29 September 2018
Author(s): Elisa Lucchini, Renato Fanin, Nichola Cooper, Francesco Zaja

Despite the improvement in understanding its pathogenesis and the introduction of novel treatment options, the management of primary immune thrombocytopenia (ITP) still remains challenging.... more


English and Italian national health services: Time for more patient-centered primary care?

29 September 2018
Author(s): Livio Garattini, Anna Padula

Primary care is the first level of contact for people to meet their health needs, so its functioning is crucial for a health care system [1]. Broadly, primary care can include a wide range of... more

The geriatric condition of frailty

22 September 2018
Author(s): Katie Palmer, Graziano Onder, Matteo Cesari

Frailty is a clinical condition characterized by a decrease of reserves and functions across multiple physiological systems, responsible for a compromised ability to cope with stressors [1]. Frailty... more

Letter to the Editor

Growing number of incident pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension patients in Latvia: a shifting epidemiological landscape? Data from a national pulmonary hypertension registry

29 September 2018
Author(s): Kristaps Sablinskis, Matiss Sablinskis, Aivars Lejnieks, Andris Skride

Pulmonary hypertension (PH) is a complex, progressing and debilitating pulmonary vascular disease associated with poor prognosis. Pulmonary arterial hypertension (PAH) and chronic thromboembolic... more

Starting anticoagulation with vitamin k antagonists alone or with concomitant low-molecular weight heparin for non-valvular atrial fibrillation

28 September 2018
Author(s): Edurne Sarrate, Francisco Gual-Capllonch, Marc Sorigue

It is well known that a majority of patients with non-valvular atrial fibrillation (NVAF) treated with vitamin K antagonists (VKA) do not benefit from bridging anticoagulation for ambulatory... more

#PatientsToo. Sexual harassment by medical professionals

27 September 2018
Author(s): Philippe Charlier

Recent articles have pointed the fact that sexual harassment is not uncommon between medical professionals [1]. Unfortunately, it seems that this harassment by faculty and staff members (that is,... more

Incidence and impact of new-onset atrial fibrillation on transcatheter mitral valve repair

26 September 2018
Author(s): Rajkumar Doshi, Krunalkumar Patel, Rupak Desai, Keyur Patel, Rajeev Gupta

Transcatheter mitral valve repair (TMVr) has been approved, in the United States, for the treatment of degenerative mitral valve regurgitation (MR) in certain high surgical risk or inoperable... more

PoliFIT-INFOcus: A pilot study exploring how to promote physical activity in older people

26 September 2018
Author(s): S. Damanti, D. Azzolino, S. Riva, A. Cano, M. Marcucci, The FOCUS Project collaborators, G. Bernardelli, C. Roncaglione, B. D'Avanzo, A. Nobili, C.M. Jarach, M. Tettamanti, M. Cesari

The amount of physical activity (PA) recommended for the elderly is the same as for adults aged 18–64 [1]; however, older people are less keen to attend gyms regularly. Exercise group-based programs... more

Legionella urinary antigen test –a contribute towards a more rational use

24 September 2018
Author(s): João Ferreira-Coimbra, Sandra Rebelo, Ana Luísa Cunha, João Tiago Guimarães, Paulo Bettencourt

Legionnaires Disease (LD) is a common cause of community acquired pneumonia (CAP). LD diagnosis is challenging due to a lack of distinctive features at presentation [1]. Inadequate diagnosis and... more

Aquagenic wrinkling and cystic fibrosis carriership: A dubious relationship

20 September 2018
Author(s): Carlo Castellani, Attilio L. Boner

Pruritic wrinkling of the palmar skin following brief contact with water, aka aquagenic wrinkling of the palms (AW), has been repeatedly described as a clinical manifestation of cystic fibrosis (CF... more

Trends in the utilization and in-hospital outcomes when using mechanical circulatory support devices for stable chronic total occlusion treated with percutaneous coronary intervention

17 September 2018
Author(s): Krunalkumar Patel, Rajkumar Doshi, Dean Decter, Jay Shah, Perwaiz Meraj

The treatment of chronic total occlusion (CTO) of coronary arteries is a challenge for physicians. In recent years, CTO treatment with percutaneous coronary intervention (PCI) has increased with... more

High fractional potassium excretion in symptomatic hyponatremia

8 September 2018
Author(s): Wim Musch, Guy Decaux

In experimental SIADH induce in man [1] or animal [2–4] it is well know that not only sodium excretion increase during a few days (particularly if it is acute), the same as been reported for... more

Narrative Review

Angioedema and emergency medicine: From pathophysiology to diagnosis and treatment

13 September 2018
Author(s): Federica Depetri, Alberto Tedeschi, Massimo Cugno

Angioedema is a self-limiting edema of the subcutaneous or submucosal tissues due to localised increase of microvascular permeability whose mediator may be histamine or bradykinin. Patients present... more

Cognitive load in internal medicine: What every clinical teacher should know about cognitive load theory

1 September 2018
Author(s): Marco Mancinetti, Sissel Guttormsen, Christoph Berendonk

Internal medicine is an appropriate example of specialties in which to teach learners clinical reasoning skills, decision-making, and analytical thinking, as well as evidence-based, patient-oriented... more

Original Article

Lung function and outcomes in emergency medical admissions

20 September 2018
Author(s): Nadim Akasheh, Declan Byrne, Peter Coss, Richard Conway, Seán Cournane, Deirdre O'Riordan, Bernard Silke

We examine the ability of pre-existing measures of Forced Expiratory Volume in 1 s (FEV1), and Diffusion Capacity for Carbon Monoxide (DLCO) to determine the subsequent 30-day mortality outcome... more

Risk of incident atrial fibrillation after a prior critical illness: A retrospective cohort study

19 September 2018
Author(s): Wei-Syun Hu, Cheng-Li Lin

This investigation aimed at assessing the issue of incident atrial fibrillation (AF) associated with acute critical illness.

Review Article

Monoclonal B-cell lymphocytosis: Does the elderly patient need a specialistic approach?

26 September 2018
Author(s): Piera Angelillo, Antonella Capasso, Paolo Ghia, Lydia Scarfò

Monoclonal B-cell lymphocytosis (MBL) is defined by the presence of a monoclonal B-cell population in the peripheral blood (PB) at a concentration of


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